This review describes recent advancements in pharmacology of neurosteroids and emphasizes the benefits of neurosteroid replacement therapy for the management of neuroendocrine disorders such …

Positive allosteric modulatory neurosteroids and synthetic analogs such as ganaxolone may be administered to prevent catamenial seizure exacerbations, in what we call neurosteroid replacement …

Apr 1, 2009 · Here, we describe treatment approaches for catamenial epilepsy and provide a rationale for an investigational approach for the perimenstrual form involving exogenous administration of …

Sep 10, 2021 · This article describes recent advancements in pharmacology of neurosteroids and emphasizes the benefits of neurosteroid replacement therapy for the management of neuroendocrine …

Here, we describe treatment approaches for catamenial epilepsy and provide a rationale for an investigational approach for the perimenstrual form involving exoge-nous administration of …

INVITED REVIEWS Neurosteroid replacement therapy for catamenial epilepsy, postpartum depression and neuroendocrine disorders in women Doodipala Samba Reddy Authors and Affiliations

Aug 1, 2021 · Neurosteroid withdrawal‐linked plasticity in extrasynaptic receptors has been shown to play a key role in catamenial seizures, anxiety, and other mood disorders.

Based on our studies in catamenial epilepsy models, we suggest that “neurosteroid replacement” may be an effective approach to prevent seizure exacerbations often seen with around the menstrual …