Brain macrophages serve diversified niches in the brain to maintain the organ’s homeostasis, and can play pathogenic roles in age-related brain disease. Hoping to one day replace dysfunctional ...
Combining a serum-free medium with a xeno-free serum replacement creates a reliable system for generating functional dendritic cells and macrophages. Myeloid cells such as dendritic cells and ...
Diffuse Alveolar Damage (DAD), a severe pathological consequence of acute lung injury triggered by factors like infection or toxins, features intense inflammatory cell infiltration and carries a high ...
Systemic lupus erythematosus (SLE) involves ongoing inflammation, tissue damage from immune complexes, and incomplete immune resolution. A key factor ...
The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism. When the liver is damaged, it has the remarkable ability to regenerate ...
In a new study using blood samples from men and women with HIV on long-term suppressive therapy, a team of researchers led by Johns Hopkins Medicine scientists reports new evidence that HIV genomes ...
Resident macrophages dwell in virtually every tissue in the body. They maintain order, ward off threats, and make repairs. The tailor their specific functions to each organ—for example, microglia in ...
A macrophage that has already fought off one infection does not return to a blank slate. It carries chemical scars, etched into the very structure of its DNA packaging, that change how it responds the ...
Chronic diabetic ulcers represent one of the most challenging complications in modern healthcare, affecting over 131 million people worldwide and generating approximately $755 billion in annual ...