A new review maps how gut microbes and their metabolites bidirectionally shape T cell immunity to drive autoimmune, ...

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the immune system: the protein molecule TRAT1 (T Cell Receptor Associated ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve ...

Cytokine signaling underlies the differentiation, activation and function of T helper (Th) cells, which orchestrate adaptive immunity. Naïve CD4+ T cells adopt specialised fates—Th1, Th2, Th17 or ...

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping ...